C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 14/48 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2232749
Disclosed are novel proteins, referred to as truncated glial cell line-derived neurotrophic factor (truncated GDNF) proteins, that promote dopamine uptake by dopaminergic cells and promote the survival of nerve cells. Also disclosed are processes for obtaining the truncated GDNF proteins by recombinant genetic engineering techniques.
L'invention porte sur de nouvelles protéines dites "GDNT tronquées" (facteur neurotrophique dérivant de lignées de cellules tronquées de glial) favorisant l'absorption de la dopamine par les cellules dopaminergiques et la survie des cellules nerveuses. Elle porte en outre sur le processus d'obtention desdites protéines à l'aide de techniques de recombinaison faisant appel au génie génétique.
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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