A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/245 (2006.01) A61K 39/27 (2006.01) C12N 7/00 (2006.01) C12N 7/06 (2006.01)
Patent
CA 2383980
The present invention relates to an equine abortion virus (EHV-1) mutant which is temperature sensitive at the body temperature of the host animal, more specifically at a temperature of 38.5 ~C or higher. The temperature sensitive mutant can be used in vaccination to protect susceptible animals against EHV-1 infection. The invention furthermore relates to live vaccines derived from said mutant.
La présente invention concerne un mutant de virus herpétique équin (EHV-1) qui est sensible à la température du corps d'un animal hôte, et plus précisément à partir d'une température de 38.5 ·C. Ce mutant thermosensible peut être utilisé dans une vaccination destinée à protéger des animaux susceptibles d'être infectés par l'EHV-1. Cette invention concerne aussi des vaccins à virus vivant dérivés de ce mutant.
Akzo Nobel N.v.
Fetherstonhaugh & Co.
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