Polymer-factor viii moiety conjugates

Details Polymer-factor viii moiety conjugates Polymer-factor viii moiety conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2517369

Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.

L'invention concerne des conjugués de groupe fonctionnel à facteur VIII et un ou plusieurs polymères hydrosolubles. Généralement, on utilise du polyéthylèneglycol ou un de ses dérivés comme polymère hydrosoluble. L'invention comprend également des compositions contenant des conjugués, des procédés de fabrication de conjugués, et des méthodes d'administration de compositions de conjugués destinées à des patients.

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