Acetic acid/thymol compositions and their use in the...

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 31/05 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2713125

A composition comprising from about 1 weight part to about 10 weight parts a saturated carboxylic acid having from 2 to about 20 carbon atoms; from about 0.1 weight parts to about 10 weight parts an antifungal compound; and from about 80 weight parts to about 99 weight parts skin-penetrating gel; wherein the saturated carboxylic acid, the antifungal compound, and the skin-penetrating gel together comprise 100 weight parts. In a particular example of the composition, the saturated carboxylic acid having from 2 to about 20 carbon atoms is acetic acid; and the antifungal compound is thymol. A method of treating onychomycosis in a patient, comprising applying the composition. The method provides a safe, effective treatment of onychomycosis.

L'invention concerne une composition qui comprend d'environ 1 partie en poids à environ 10 parties en poids d'un acide carboxylique saturé ayant de 2 à environ 20 atomes de carbone; d'environ 0,1 partie en poids à environ 10 parties en poids d'un composé antifongique; et d'environ 80 parties en poids à environ 99 parties en poids d'un gel pénétrant la peau. L'acide carboxylique saturé, l'agent antifongique et le gel pénétrant la peau constituent ensemble 100 parties en poids de la composition. Dans un exemple particulier de la composition, l'acide carboxylique saturé ayant de 2 à environ 20 atomes de carbone est l'acide acétique et le composé antifongique est le thymol. Une méthode pour traiter l'onychomycose chez un patient comprend l'application de la composition. La méthode constitue un traitement sûr et efficace contre l'onychomycose.

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