Substituted n-aminoalkylmethane sulfanilide as antispasmodica

C - Chemistry – Metallurgy – 07 – D

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C07D 295/13 (2006.01) A61K 31/18 (2006.01) A61K 31/395 (2006.01) C07C 311/08 (2006.01) C07D 295/155 (2006.01)

Patent

CA 2113032

Abstract Substituted N-aminoalkylmethane sulfanilide as antispasmodica Substituted N-aminoalkylmethane sulfanilide of formula (I), their solutions and pharmaceutically acceptable addition salts, their pharmaceutical compositions and their therapeutic use. In formula (I) Y represents hydrogen, cyano, nitro, amino, acetamide or halogen; n is an integer between 2 and 4, R1 and R2, equal or different, are alkyl-(C1-C4) or they are connected together and with the N-atom thereby forming a 1-pyrrolidinyl, 1-piperidinyl, 1-piperazinyl, 4-methyl-1-piperazinyl, 4-ethylpiperazinyl, 4-propylpiperazinyl, 1-homopiperidinyl or 4-morpholine residue. The products of formula (I) are used as antispasmodic agents. Image (I)

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