Intercellular adhesion molecule-3 and its binding ligands

Details Intercellular adhesion molecule-3 and its binding ligands Intercellular adhesion molecule-3 and its binding ligands

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2110387

2110387 9222323 PCTABS00018 The present invention relates to intercellular adhesion molecules (ICAM-3) which is involved in the process through which leukocytes recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, screening assays for identifying such molecules and antibodies capable of binding such molecules. The invention also includes therapeutic and diagnostic uses for adhesion molecules and for the antibodies that are capable of binding them.

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