Rfkbp: a novel prolyl isomerase and rapamycin/fk506 binding...

Details Rfkbp: a novel prolyl isomerase and rapamycin/fk506 binding... Rfkbp: a novel prolyl isomerase and rapamycin/fk506 binding...

C - Chemistry, Metallurgy

12

N

C12N 15/61 (2006.01) C07H 21/04 (2006.01) C12N 9/90 (2006.01) C12Q 1/533 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2102117

2102117 9219745 PCTABS00017 A novel prolyl isomerase, RFKBP, which binds FK506 and rapamycin with quantitatively significant selectivity and does not bind cyclosporin A and the molecular cloning of a cDNA (SEQ ID NO: 6) whose sequence predicts a chemically determined amino acid sequence of RFKBP. The deduced protein of the cDNA is 142 amino acid residues in length (SEQ ID NO: 7).

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