C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2481560
This invention discloses pyrimidine compounds, and pharmaceutically acceptable salts, solvates and prodrugs thereof, useful in therapeutically and/or prophylactically treating patients with cancer by inhibiting receptor tyrosine kinases and/or dihydrofolate reductase and/or thymidylate synthase. The compounds, and methods of using these compounds, are disclosed.
L'invention concerne des composés de pyrimidine, ainsi que leurs sels pharmaceutiquement acceptables, leurs solvates et leurs promédicaments, utilisés pour le traitement thérapeutique et/ou prophylactique de patients atteints d'un cancer, par inhibition des récepteurs tyrosine kinases et/ou de la dihydrofolate réductase et/ou de la thymidylate synthase. L'invention concerne également des procédés d'utilisation de ces composés.
Duquesne University Of The Holy Ghost
Smart & Biggar
LandOfFree
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