C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2216878
The present invention relates to defective recombinant viruses which contain at least one inserted gene encoding all or part of the protein GAX or of a variant of this protein, and to their therapeutic use, in particular for treating post-angioplastic restenosis.
L'invention concerne des virus recombinants défectueux contenant au moins un gène inséré codant tout ou partie de la protéine GAX ou d'une variante de cette protéine, ainsi que leur utilisation thérapeutique, en particulier, pour traiter une resténose post-angioplasique.
Branellec Didier
Denefle Patrice
Isner Jeffrey M.
Walsh Kennneth
Case Western Reserve University
Goudreau Gage Dubuc
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