Preparation of microparticles

Details Preparation of microparticles Preparation of microparticles

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/72 (2006.01) A61K 49/22 (2006.01) B01J 13/04 (2006.01) B01J 13/12 (2006.01)

Patent

CA 2113901

Solid microspheres or hollow (i.e. gas or vapour filled) microcapsules, for example of amylodextrin are prepared by form- ing a shell from a water-soluble starch derivative around a solid or liquid core and subsequently removing the core. The core may be a volatile oil such as perfluorohexane. The microspheres or microcapsules may be made by an oil/water/oil double emulsion followed by chemical or heat hardening to render them water-insoluble. The microspheres can be used for nasal delivery systems and the microcapsules for echocardiography.

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