C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2430745
A novel gene expressed selectively by osteoblast lines is provided. Expression of the gene is highly restricted to cells of osteoblast lineage, including precursor cells. Also provided is a method for promoting bone formation by providing agents that bind to the novel gene within osteoblast cells to stimulate bone formation.
L'invention concerne un nouveau gène exprimé de manière sélective par des lignées ostéoblastiques. L'expression de ce gène est hautement restreint aux cellules de lignée ostéoblastique, y compris des cellules précurseurs. L'invention concerne également un procédé permettant de promouvoir la formation osseuse en fournissant des agents qui se lient au nouveau gène à l'intérieur des cellules pour stimuler la formation osseuse.
de Crombrugghe Benoit
Nakashima Kazuhisa
Zhou Xin
Board Of Regents The University Of Texas System
Goudreau Gage Dubuc
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