Novel cycloalkane carboxamides as factor xa inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/4427 (2006.01) A61K 31/5377 (2006.01) A61P 7/02 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2619912

The invention is concerned with novel cycloalkane carboxamides of Formula (I) wherein X, X1, Y, Y1~, R1~~, R1, R2, R3, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.

La présente invention concerne de nouveaux cycloalcanecarboxamides de Formule (I) où X, X1, Y, Y1~, R1~~, R1, R2, R3, m et n sont tels que définis dans la description et dans les revendications, de même que des sels de qualité physiologique desdits composés. Ces composés inhibent le facteur de coagulation Xa et peuvent être employés en tant que médicaments.

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