Method of modifying the genome of gram-positive bacteria by...

Details Method of modifying the genome of gram-positive bacteria by... Method of modifying the genome of gram-positive bacteria by...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12N 15/77 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2439684

The invention relates to a novel method of modifying the genome of gram- positive bacteria, to said bacteria and to novel vectors. The invention especially relates to a method of modifying Corynebacteria or Brevibacteria using a novel marker gene that has a conditionally negative dominant effect.

L'invention concerne un procédé de modification du génome de bactéries Gram positif, ainsi que lesdites bactéries et de nouveaux vecteurs. L'invention concerne en particulier un procédé de modification de Corynebacterium ou de Brevibacterium au moyen d'un nouveau gène marqueur à dominante conditionnellement négative dans les bactéries.

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