A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
A61F 2/06 (2006.01)
Patent
CA 2574972
An implantable drug-releasing medical device (10), as seen in Figure 4A, fabricated of a metallic or pseudometallic film is disclosed.The metallic or pseudometallic film being made of biocompatible material having a plurality of micropeferations (20) which pass through the film in a pattern that imparts fabric-like qualities to the device and/or permits the geometric deformation of the medical device. The implantable medical device is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperferations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical device is suitable for use as endoluminal or surgical grafts and may be used, for example, as vascular grafts, stent grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
La présente invention a trait à des dispositifs médicaux implantables de libération de médicaments fabriqués en films métalliques ou pseudo-métalliques comprenant une pluralité de micro-perforations traversant le film en une configuration qui procure des caractéristiques de tissu au dispositif et/ou permet la déformation géométrique du dispositif médical. Le dispositif médical implantable est de préférence fabriqué par dépôt sous vide de matériaux métalliques et/ou pseudo-métalliques en des structures monocouche ou multicouche avec une pluralité de micro-perforations soit formées en cours de dépôt ou suite au dépôt par l'élimination sélective de sections du film déposé. Le dispositif médical implantable est apte à être utilisé comme greffons endoluminaux ou chirurgicaux et peut être utilisé, par exemple, comme greffons vasculaires, greffons endovasculaires, greffons cutanés, valves, greffons osseux, pièces chirurgicales, conduits non vasculaires, feuillets valvulaires, filtres, membranes d'occlusion, sphincters, tendons et ligaments artificiels.
Bailey Steven R.
Banas Christopher E.
Boyle Christopher T.
Palmaz Julio C.
Advanced Bio Prosthetic Surfaces Ltd.
Blake Cassels & Graydon Llp
LandOfFree
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