Percutaneously absorbable preparation

Details Percutaneously absorbable preparation Percutaneously absorbable preparation

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61P 25/28 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2725484

The present invention provides a percutaneously absorbable preparation comprising 2-[(1-benzylpiperidin-4-yl) methyl]-5,6-dimethoxyindan-1-one and/or a hydrochloride thereof wherein the percuneously absorbable preoaration is able to administer to a patient such that Cmax per unit surface area of the percutaneously absorbable preparation is 0.025 to 0.5 ng/ml.cndot.cm2 in a plasma concentration profile.

L'invention porte sur une préparation transdermique comprenant du 2-[(1-benzyl-4-pipéridinyl)méthyl]-5,6-diméthoxyindan-1-one et/ou un chlorhydrate de celui-ci. La préparation transdermique présente un profil de concentration sérique tel que le Cmax de la préparation transdermique par unité de surface passe de 0,025 à 0,5 ng/ml*cm2 lors de l'administration à un patient.

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