Implantable biocompatible immttnoisolatory vehicle for...

A - Human Necessities – 61 – K

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Details

A61K 48/00 (2006.01) A61K 35/44 (2006.01) A61K 38/18 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2627543

The present invention relates to devices comprising a composition of human cells secreting a therapeutically effective amount of GDNF (Glial cell-line- derived neurotrophic factor) encapsulated in a device comprising a core and a semipermeable membrane allowing for the diffusion of GDNF protein. The human cells are from one cell line.

La présente invention a pour objet des appareils qui comprennent une composition de cellules humaines sécrétant une quantité thérapeutiquement efficace de GDNF (Glial cell-line-derived neurotrophic factor) encapsulée dans un appareil qui consiste en un noyau et une membrane semi-perméable et qui permet la diffusion de la protéine GDNF. Les cellules humaines proviennent d'une seule lignée cellulaire.

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