Drug delivery system for administration of poorly water...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/20 (2006.01) A61K 9/14 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2709266

This invention relates to a drug delivery system for administration of poorly water soluble pharmaceutically active substance, a pharmaceutical composition comprising such a drug delivery system, and a method for the preparation of such a drug delivery system. The invention also relates to a method for controlling the particle size and/or particle shape and/or particle size distribution in such a drug delivery system, and to a method for increasing the drug loading capacity of the particles. Furthermore the invention also relates to the use of such a drug delivery system for the preparation of a medicament for the treatment of cancer.

Cette invention concerne un système d'administration de médicament pour administrer une substance pharmaceutiquement acceptable faiblement hydrosoluble, une composition pharmaceutique comprenant un tel système d'administration de médicament, et un procédé pour la préparation d'un tel système d'administration de médicament. Cette invention concerne un procédé permettant de réguler la taille des particules et/ou la forme des particules et/ou la granulométrie dans un tel système d'administration de médicament. L'invention concerne également un procédé permettant d'augmenter la capacité de charge en médicament des particules. En outre, cette invention concerne également l'utilisation d'un tel système d'administration de médicament pour la préparation d'un médicament destiné au traitement du cancer.

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