Use of caspase-8 inhibitors for modulating hematopoiesis

A - Human Necessities – 61 – K

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Details

A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/02 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2543565

A method of inhibiting hematopoiesis in a subject is provided. The method is effected by downregulating an expression or activity of caspase-8 in the subject thereby inhibiting hematopoiesis therein.

La présente invention concerne un procédé permettant d'inhiber l'hématopoïèse chez un individu. A cet effet, on fait diminuer l'expression ou l'activité de la caspase-8 chez l'individu considéré, ce qui inhibe l'hématopoïèse.

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