Method of reducing morbidity and the risk of mortality

Details Method of reducing morbidity and the risk of mortality Method of reducing morbidity and the risk of mortality

A - Human Necessities

61

K

A61K 31/4453 (2006.01) A61K 31/00 (2006.01) A61K 31/138 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 31/407 (2006.01) A61K 31/4439 (2006.01) A61K 31/451 (2006.01) A61K 31/453 (2006.01) A61K 31/4725 (2006.01) A61K 31/55 (2006.01) A61P 9/00 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2331059

This invention relates to methods, pharmaceutical compositions and kits useful in reducing cardiovascular morbidity and the risk: of mortality in men and post-menopausal women and morbidity and the risk of mortality in post- menopausal women from the combined reduction of breast cancer, osteoporosis and cardiovascular disease by the administration of estrogen agonists / antagonists. The compositions are comprised of an estrogen agonist / antagonist and a pharmaceutically acceptable vehicle, carrier or diluent. The compositions and methods of treatment are effective while substantially reducing the concomitant liability of adverse effects associated with estrogen administration.

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