Insoluble carrier for use in anti-phospholipid antibody...

Details Insoluble carrier for use in anti-phospholipid antibody... Insoluble carrier for use in anti-phospholipid antibody...

G - Physics

01

N

G01N 33/545 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2741801

The present invention has an object to provide an insoluble carrier for an antiphospholipid antibody detection reagent having a high reactivity. The present invention also has an object to provide an antiphospholipid antibody detection reagent, and a method of detecting an antiphospholipid antibody. The present invention directs to an insoluble carrier for an antiphospholipid antibody detection reagent, having a zeta potential of lower than -45 mV in the case that the insoluble carrier is suspended in a 20 mmol/L aqueous sodium phosphate solution with a pH of 7.4 so that the resulting suspension has a solids concentration of 0.1%.

La présente invention concerne un véhicule insoluble qui peut être utilisé dans un réactif de mesure danticorps anti-phospholipide ayant une réactivité élevée.  La présente invention concerne en outre un réactif de mesure danticorps anti-phospholipide.  La présente invention concerne en outre un procédé pour mesurer un anticorps anti-phospholipide. La présente invention concerne spécifiquement un véhicule insoluble pour utilisation dans un réactif de mesure danticorps anti-phospholipide, qui est caractérisé en ce quune suspension préparée par mise en suspension du véhicule insoluble dans une solution aqueuse de phosphate de sodium à 20 mmoles/l (pH 7,4) de sorte que la teneur en matières solides de la suspension atteigne 0,1 % a un potentiel zêta inférieur à -45 mV.

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