A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 277/34 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2379662
Fused-heterocycle compounds of general formula (I) or pharmacologically acceptable salts thereof, useful as therapeutic and preventive agents for cancer, wherein X is a benzimidazole ring group which may have one to five substituents selected from among alkyl groups and so on; Y is oxygen or sulfur; Z is thiazolidine-2,4-dione-5-ylmethyl or the like; R is hydrogen or the like; and m is an integer of 1 to 5.
L'invention concerne des composés hétérocycliques fusionnés ou leurs sels acceptables sur le plan pharmaceutique, qui sont utiles en tant qu'agents thérapeutiques et préventifs du cancer, et qui sont représentés par la formule générale (I), dans laquelle X est un groupe à noyau benzimidazole pouvant comprendre entre un et 5 substituants sélectionnés dans des groupes alkyles ; Y est oxygène ou soufre ; Z est thiazolidine-2, 4-dione-5-ylméthyle ou analogue ; R est hydrogène ou analogue ; et m est un nombre entier compris entre 1 et 5.
Fujita Takashi
Fujiwara Kosaku
Kurakata Shinichi
Marks & Clerk
Sankyo Company Limited
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