Gene sequences of rubella virus associated with attenuation

Details Gene sequences of rubella virus associated with attenuation Gene sequences of rubella virus associated with attenuation

C - Chemistry, Metallurgy

12

N

C12N 15/40 (2006.01) A61K 39/20 (2006.01) C07K 14/19 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 9/50 (2006.01) C12N 15/52 (2006.01) C12N 15/54 (2006.01) C12N 15/57 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2238660

The complete sequence of the Cendehill rubella strain is provided, including infectious cDNA clones derived therefrom. Portions of the Cendehill genome responsible for decreased arthritogenicity and immunogenicity are identified. Modified rubella cDNA, RNA and virus is provided incorporating Cendehill and non-Cendehill sequences.

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