Reagents and methods for identifying and modulating...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2365908

This invention provides methods and reagents for identifying genes involved in cell cycle progression, growth promotion, modulation of apoptosis, cellular senescence and aging, and methods for identifying compounds that inhibit or potentiate cellular senescence, regulated by p21.

L'invention concerne des procédés et réactifs d'identification de gènes impliqués dans la progression du cycle cellulaire, le développement de la croissance, la modulation de l'apoptose, la sénescence et le vieillissement des cellules; elle concerne également des procédés d'identification de composés inhibant ou potentialisant la sénescence des cellules régulée par p21.

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