Medicament in a multilayer form

Details Medicament in a multilayer form Medicament in a multilayer form

A - Human Necessities

61

K

A61K 9/28 (2006.01)

Patent

CA 2570277

The invention relates to a medicament in a multilayer form, containing a) a core with a pharmaceutical agent, b) an inner coating, 50 to 95 percent by weight of which are composed of a (co)polymer comprising 95 to 100 percent by weight of radically polymerized vinylic monomers with neutral side groups and 0 to 5 percent by weight of monomers with anionic side groups, c) an outer coating made of a copolymer comprising 75 to 95 percent by weight of radically polymerized C1 to C4 alkyl esters of acrylic acid or methacrylic acid and 5 to 25 percent by weight of (meth)acrylate monomers with an anionic group in the alkyl radical. Said medicament further contains 5 to 30 percent by weight of common pharmaceutical auxiliaries, particularly emollients. The inventive medicament is characterized in that the inner coating contains 5 to 50 percent by weight of common pharmaceutical auxiliaries which are no expanding agents while the amount of expanding agents provided is less than 5 percent by weight.

L'invention concerne un médicament de forme multicouche comprenant a) un noyau ayant un principe actif pharmaceutique, b) un revêtement interne contenant 50 à 95 % en poids d'un copolymère qui se compose de 95 à 100 % en poids de monomères vinyliques radicalement polymérisés ayant des groupes latéraux neutres et de 0 à 5 % en poids de monomères ayant des groupes latéraux anioniques, c) un revêtement externe constitué d'un copolymère qui se compose de 75 à 95 % en poids d'esters d'alkyle C1- à C4 radicalement polymérisés d'acides acryliques ou méthacryliques et de 5 à 25 % en poids de monomères de (méth)acrylate ayant un groupe anionique dans le reste d'alkyle et enfin 5 à 30 % en poids de principes actifs pharmaceutiquement courants, notamment de plastifiants. Cette forme de médicament est caractérisée en ce que le revêtement interne contient 5 à 50 % en poids de principes actifs pharmaceutiquement usuels qui ne sont pas des agents porogènes et ne contiennent des agents porogènes que dans une quantité maximale de 5 % en poids.

Affiliated with

Also associated with

Rating

Medicament in a multilayer form does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Medicament in a multilayer form, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medicament in a multilayer form will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1855829