A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/07 (2006.01) A61K 31/05 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2601278
The invention relates to compounds capable of inhibiting the visual cycle and/or dark adaptation and their use for treatment and prevention of non- degenerative retinal diseases with specific emphasis on the prevention and treatment of diabetic retinopathy, retinopathy of prematurity, branch retinal vein occlusion, central retinal vein occlusion, open-angle glaucoma, veovascular glaucoma, and other diseases of the retinal and/or optic nerve where an imbalance between metabolic demand and blood supply contribute to the development of tissue damage. The invention furthermore relates to pharmaceutical compositions comprising such compounds.
L'invention concerne des composés capables d'inhiber le cycle visuel et/ou l'adaptation à l'obscurité et leur utilisation dans le traitement et la prévention de maladies rétiniennes non dégénératives avec un accent particulier sur la prévention et le traitement de la rétinopathie diabétique, de la rétinopathie de prématurité, de l'occlusion artérielle rétinienne ramifiée, de l'occlusion artérielle rétinienne centrale, du glaucome chronique, du glaucome néovasculaire, et d'autres maladies de la rétine et/ou du nerf optique dans lesquels un déséquilibre entre la demande métabolique et l'irrigation sanguine contribuent au développement de dommages causés aux tissus. L'invention concerne, en outre, des compositions pharmaceutiques contenant ces composés.
Deeth Williams Wall Llp
Larsen Lars Michael
LandOfFree
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