Ortho-substituted benzoylguanidines, process for their...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/22 (2006.01) A61K 31/215 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 323/44 (2006.01) C07D 207/30 (2006.01) C07D 213/60 (2006.01) C07D 215/48 (2006.01) C07D 217/22 (2006.01) C07D 307/34 (2006.01) C07D 333/04 (2006.01)

Patent

CA 2206758

Ortho-substituted benzoylguanidines of the formula I Image in which R(1) to R(5) have the meanings given in the claims, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and for infarct treatment and also for the treatment of angina pectoris. They also inhibit in a preventive manner the pathophysiological processes in the formation of ischemically induced damage, in particular in the illicitation of ischemically induced cardiac arrhythmias.

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