Novel atropisomers of...

Details Novel atropisomers of... Novel atropisomers of...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/505 (2006.01) C07D 471/04 (2006.01) C07D 473/30 (2006.01) C07D 475/02 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2246595

The present invention relates to novel atropisomers of 2,3-disubstituted-(5,6)-heteroarylfused-pyrimidin-4-ones of the formula: Image (wherein V, X, Y, Z are all C or one is N and the others are C; R1, R2, R3, R4 and R5 are each H or substituent; ring A' is fused 5- or 6-membered heteroaromatic ring; and R6 is phenyl or 5- or 6-membered heterocycle), pharmaceutical compositions containing such compounds, use of such compounds to treat neurodegenerative, psychotropic, and drug and alcohol induced central and peripheral nervous system disorders.

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