Aptamer against il-17 and use thereof

Details Aptamer against il-17 and use thereof Aptamer against il-17 and use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 9/107 (2006.01) A61K 31/7105 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 37/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2730796

Provided is a high-quality aptamer against IL-17. An aptamer possessing an inhibitory activity against IL-17; a complex comprising an aptamer possessing a binding activity or inhibitory activity against IL-17 and a functional substance (for example, affinity substances, substances for labeling, enzymes, drug delivery vehicles, drugs and the like); a pharmaceutical drug, cell migration inhibitor, diagnostic reagent, labeling agent and the like comprising an aptamer possessing a binding activity or inhibitory activity against IL-l7, or a complex comprising the aptamer and a functional substance; a cell migration inhibitor, a diagnostic reagent, a labeling agent and the like

L'invention porte sur un aptamère de haute qualité pour IL-17 et qui est, par exemple, un aptamère doté dune activité inhibitrice à l'encontre d'IL-17, sur un composé qui contient une substance fonctionnelle (telle qu'une substance d'affinité, une substance de marquage, une enzyme, un milieu d'administration de médicament ou un médicament) et un aptamère doté dune activité de liaison ou dune activité inhibitrice à l'encontre d'IL-17, ou sur un médicament, un agent de diagnostic ou un agent de marquage qui contient un aptamère doté dune activité de liaison ou dune activité inhibitrice à l'encontre d'IL-17, ou un composé dudit aptamère et une substance fonctionnelle.

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