Compounds as the estrogen-related receptor modulators and...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) C07D 239/86 (2006.01) C07D 239/88 (2006.01) C07D 239/90 (2006.01) C07D 239/91 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2739379

The compounds according to formula (I), their pharmaceutically acceptable acid or base addition salts, and the uses thereof. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for preparing medicaments for modulating estrogen related receptors (ERR), and treating metabolic diseases, such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity. The substituents of the formula are defined in the description. (see formula I)

Linvention concerne un composé chimique de formule générale I, son sel alcalin ou acide acceptable sur le plan de la pharmacologie et son utilisation. Ledit composé chimique et son sel alcalin ou acide acceptable sur le plan de la pharmacologie peuvent être utilisés dans la préparation dun médicament pouvant réguler les récepteurs associés aux récepteurs des strogènes (ERR) ou traiter lhyperlipidémie, la stéatose hépatique, lhyperglycémie, le diabète, lobésité et dautres maladies métaboliques similaires. Chaque radical de la formule I est tel que défini dans la description.

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