Trans-3-aza-bicyclo[3.1.0]hexane derivatives

Details Trans-3-aza-bicyclo[3.1.0]hexane derivatives Trans-3-aza-bicyclo[3.1.0]hexane derivatives

C - Chemistry, Metallurgy

07

D

C07D 209/52 (2006.01) A61K 31/403 (2006.01) A61P 25/00 (2006.01) C07D 405/12 (2006.01) C07D 417/14 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2693817

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.

L'invention porte sur de nouveaux dérivés de trans-3-aza-bicyclo[3.1.0]hexane représentés par la formule (I) dans laquelle A, B, n et R1 sont tels que définis dans la description, et sur l'utilisation de tels composés, ou de sels pharmaceutiquement acceptables de tels composés, comme médicaments, notamment comme antagonistes du récepteur de l'orexine.

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