Water-soluble films comprising low-viscosity alginates

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/36 (2006.01) A61K 9/70 (2006.01) A61K 36/03 (2006.01) A61P 25/34 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2633878

A film comprising as a film-forming agent an alginate salt of monovalent cation or a mixture of alginate salts containing at least one alginate salt of monovalent cation, the film-forming agent being such that a 10% aqueous solution thereof at a temperature of 20~C has a viscosity of 100-1000 mPas, as measured at a shear rate of 20 rpm by use of a Brookfield viscometer with a spindle No. 2. A method of preparing the film. The film is useful for delivery of active ingredients to a mammal.

La présente invention concerne une pellicule comprenant, en tant qu~agent filmogène, un sel alginate de cation monovalent ou un mélange de sels alginates contenant au moins un sel alginate de cation monovalent, l~agent filmogène étant tel qu~une solution aqueuse à 10 % de celui-ci, à une température de 20 °C, présente une viscosité de 100-1000 mPas, telle que mesurée à une vitesse de cisaillement de 20 tr/min à l~aide d~un viscosimètre Brookfield équipé d~une tige numéro 2. L~invention concerne également un procédé de préparation de la pellicule. La pellicule est utile pour l~administration d~ingrédients actifs à un mammifère.

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