Therapeutic administration of hemoglobin in cardiac arrest

A - Human Necessities – 61 – K

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A61K 38/42 (2006.01)

Patent

CA 2233917

Administration of stroma-free cross-linked hemoglobin during standard cardiac pulmonary resuscitation procedures enhances return of spontaneous circulation following electrical defibrillation. The difficulty in restoring spontaneous circulation directly correlates with a generally poor prognosis in cases of cardiac arrest. The therapeutic effect of hemoglobin as an adjunct to conventional treatment may thereby improve survival.

L'administration d'hémoglobine réticulée exempte de stroma au cours d'interventions standards de réanimation cardio-respiratoire favorise le retour de la circulation spontanée après défibrillation électrique. La difficulté de rétablir la circulation spontanée correspond à un pronostic généralement défavorable dans les cas d'arrêt cardiaque. L'effet thérapeutique de l'hémoglobine utilisée comme traitement d'appoint à un traitement conventionnel peut ainsi prolonger la durée de vie.

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