Methods for the detection and treatment of aberrant prion...

Details Methods for the detection and treatment of aberrant prion... Methods for the detection and treatment of aberrant prion...

C - Chemistry, Metallurgy

12

N

C12N 9/02 (2006.01) C12Q 1/26 (2006.01)

Patent

CA 2756908

The invention relates to methods and tools for detecting and treating patients suffering from aberrant prion functioning or Aberrant Prion Disease (APD), methods for determining the presence of aberrant prion functioning-inducing agents in a sample and to methods for determining the appropriate therapy for a patient having symptoms of aberrant prion functioning based on detecting aberrant NADH oxidase activity.

La présente invention concerne des méthodes et des outils de détection et de traitement de patients souffrant d'un fonctionnement du prion aberrant ou de la maladie du prion aberrant (APD). L'invention porte en outre sur des méthodes permettant de déterminer la présence d'agents induisant le fonctionnement du prion aberrant dans un échantillon, et sur des méthodes permettant de déterminer la thérapie appropriée pour un patient présentant des symptômes de fonctionnement de prion aberrant, sur la base de la détection d'une activité de NADH oxydase aberrante.

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