Capping enzyme of flavivirus and utilization of this protein...

Details Capping enzyme of flavivirus and utilization of this protein... Capping enzyme of flavivirus and utilization of this protein...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/52 (2006.01) C07H 21/00 (2006.01) C07K 16/08 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/31 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2449157

The present invention concerns an isolated and purified polypeptide capable of acting as a guanylyltransferase and methyltransferase comprising capping enzyme of flavivirus (CEF). The present invention also concerns the use of such polypeptide to identify biologically active molecule which can be used in the treatment or the prevention of diseases resulting from Flavivirus infection.

La présente invention concerne un polypeptide isolé et purifié d'une enzyme de coiffage du flavivirus (CEF) comprenant la guanylyltransférase et la méthyltransférase. Cette invention concerne également l'utilisation d'un tel polypeptide pour identifier une molécule biologiquement active pouvant être utilisée dans le traitement ou la prévention de maladies résultant d'une infection par le Flavivirus.

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