A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/534 (2006.01) A61K 31/352 (2006.01) A61K 31/37 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2734523
Isolated compounds and combinations of isolated compounds isolated from Scutellaria barbata D. Don are effective in the generation of reactive oxygen species, induction of DNA damage and induction of apoptosis in cancer cells. The compounds and combinations may be prepared as pharmaceutical compositions for administration to mammals, such as humans, for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers.
La présente invention concerne des composés isolés et des combinaisons de composés isolés à partir de Scutellaria barbata D. Don, efficaces dans la production despèces doxygène réactif, linduction de dommage de lADN et linduction de lapoptose dans des cellules cancéreuses. Lesdits composés et lesdites combinaisons peuvent être préparés en tant que compositions pharmaceutiques destinées à être administrées à des mammifères, tels que des humains, dans le traitement de cancers solides, tels que des cancers de lépithélium. De tels cancers de lépithélium incluent le cancer du sein et les cancers des ovaires.
Bionovo Inc.
Smart & Biggar
LandOfFree
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