Composition and method for reducing gastro-intestinal...

A - Human Necessities – 61 – K

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A61K 38/47 (2006.01) A23L 1/03 (2006.01) A23L 1/305 (2006.01)

Patent

CA 2055506

A composition is provided for ingestion by mammals for in vivo conversion of alpha-D-galactoside comprising an amount of alpha-galactosidase effective to hydrolyze alpha-D- galactoside to D- galactose, and non-toxic, ingestible excipient(s) for said alpha-galactoside. Gastric distress in mammals due to ingestion of foods containing alpha-D-galactoside may be reduced by ingesting the foregoing composition of alpha-galactosidase and non-toxic, ingestible excipient contemporaneously with the ingestion of said food in an amount effective to hydrolyze the alpha-D- galactoside to D-galactose.

Cette composition peut être ingérée par des mammifères afin de convertir in vivo l'alpha-D-galactoside. La composition comprend une quantité d'alpha-galactoside suffisante pour hydrolyser l'alpha-D-galactoside et le transformer en D-galactose, ainsi que des excipients digestibles non toxiques de l'alpha-galactosidase. Les douleurs gastriques chez les mammifères dues à l'ingestion d'aliments qui contiennent de l'alpha-D-galactoside peuvent être réduits par l'ingestion d'une quantité suffisante de ladite composition d'alpha-galactoside et d'excipients digestibles non toxiques en quantité suffisante pour hydrolyser l'alpha-D-galactoside et le transformer en D-galactose, ces produits étant ingérés en même temps que des aliments qui contiennent l'alpha-D-galactoside.

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