Novel xanthine phosphoribosyl transferase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) A61K 39/09 (2006.01) A61K 48/00 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2237047

The invention provides xanthine phosphoribosyl transferase polypeptides and DNA (RNA) encoding xanthine phosphoribosyl transferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing xanthine phosphoribosyl transferase polypeptides to screen for antibacterial compounds.

L'invention fournit des polypeptides de xanthine-phosphoribosyl transférase et de l'ADN (ARN) codant pour ces polypeptides, ainsi que des méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes pour utiliser les polypeptides de xanthine-phosphoribosyl transférase dans le dépistage de composés antibactériens sont également dévoilées.

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