C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/09 (2010.01)
Patent
CA 2753526
Disclosed is a novel cell mass derived from a cancer tissue, which can reflect the in vivo behavior of a cancer cell correctly. Also disclosed is a process for preparing the cell mass. Specifically disclosed is a cell mass derived from a cancer tissue, which is an isolated product that is isolated from a cancer tissue obtained from an individual as a mass containing at least three cancer cells or a culture of the isolated product and which can retain a proliferation ability in vitro. The cell mass derived from a cancer tissue is produced by, for example, a preparation process comprising the steps of. treating a pulverized product of a cancer tissue removed from a living body with an enzyme; and selecting and collecting a mass containing at least three cancer cells among from an enzymatic treatment product.
L'invention porte sur une nouvelle masse cellulaire issue d'un tissu cancéreux, qui peut refléter le comportement in vivo d'une cellule cancéreuse de façon correcte. L'invention porte également sur un procédé de préparation de la masse cellulaire. De façon spécifique, est divulguée une masse cellulaire issue d'un tissu cancéreux, qui est un produit distinct, lequel est isolé à partir d'un tissu cancéreux obtenu à partir d'un individu en tant que masse contenant au moins trois cellules cancéreuses ou une culture du produit isolé et qui peut conserver une aptitude à la prolifération in vitro. La masse cellulaire issue d'un tissu cancéreux est obtenue, par exemple, par un procédé de préparation comprenant les étapes consistant à : traiter par une enzyme un produit pulvérisé d'un tissu cancéreux retiré d'un corps vivant; et sélectionner et recueillir une masse contenant au moins trois cellules cancéreuses parmi un produit de traitement enzymatique.
Inoue Masahiro
Ohue Masayuki
Osaka Prefectural Hospital Organization
Rei Medical Co. Ltd.
Smart & Biggar
LandOfFree
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