Process of producing .alpha.-l-aspartyldipeptide amide...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/072 (2006.01)

Patent

CA 2166246

.alpha.-L-aspartyldipeptide amide derivatives are produced by reacting an L-aspartic acid derivative with an alkyl chloroformate to form a mixed anhydride, condensing the mixed anhydride thus obtained with an amino acid amide derivative to obtain a protected .alpha.-L-aspartyldipeptide amide derivative which is thereafter hydrolyzed under acidic conditions. The .alpha.-L-aspartyldipeptide amide derivatives produced according to the invention are useful as artificial sweeteners.

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