Unsymetrical bis-imides as anticancer agents

Details Unsymetrical bis-imides as anticancer agents Unsymetrical bis-imides as anticancer agents

C - Chemistry, Metallurgy

07

D

C07D 221/18 (2006.01) A61K 31/435 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2155856

This invention relates to unysymmetrical bis-imide compounds, and pharmaceutically acceptable salts thereof, of formula (i) including (R,R)-1-[2-(acenaphthene-5,6-dicarboximido)propylamino]-2-[2-(3-nitronaphthalene-1,8-dicarboximido)propylamino]ethane, processes for the preparation of such compounds, pharmaceutical compositions containing such compounds, and methods of using such compounds to treat cancer, particularly solid tumor carcinomas, in mammals.

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