Indole derivatives as antitumoural compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 403/04 (2006.01) A61K 31/495 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2628624

Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R1, R2, R3, R4, R5, R6, R7, n and the dotted line take permitted meanings can be obtained from a tunicate of the family Polyclinidae, genus Aplidium, species cyaneum, and the invention further provides derivatives thereof.

Des composés antitumoraux de formule générale (I) ; où Ar représente un groupement hétérocyclique de formule (a) et R1, R2, R3, R4, R5, R6, R7, n et le segment en pointillés prennent des valeurs permises, peuvent être obtenus à partir d'un tunicate de la famille Polyclinidae, genre Aplidium, espèce cyaneum. La présente invention concerne en outre des dérivés de ces composés.

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Profile ID: LFCA-PAI-O-1862006

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