Immunosuppressive cyclosporin analogs with modified amino...

C - Chemistry – Metallurgy – 07 – K

Patent

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530/7.64, 167/10

C07K 7/64 (2006.01) A61K 38/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2036963

9080S/5507A 18018 TITLE OF THE INVENTION NOVEL IMMUNOSUPPRESSIVE CYCLOSPORIN ANALOGS WITH MODIFIED AMINO ACIDS AT POSITION-8 ABSTRACT OF THE INVENTION New immunosuppressive cyclosporin analogs are disclosed consisting of [dehydro-Ala]8 cyclosporins and derived therefrom cyclosporins having a sulfur containing amino acid at position-8.

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