Processes for preparing sulfonylureas

C - Chemistry – Metallurgy – 07 – D

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C07D 239/28 (2006.01) C07C 311/65 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2091138

HOE 92/F 059 Abstract of the disclosure Processes for preparing sulfonylureas Compounds of the formula I or salts thereof, Image in which X is oxygen, -O-NR2- or -SO2-NR2-, and Y is N or CH, R1 is (C1-C6)alkyl, (C2-C6)alkenyl or (C2-C6)alkynyl, which are in each case optionally substituted, or, in the case where X = oxygen, also (subst.) phenyl, R2 is H, (C1-C6)alkyl, (C2-C8)alkenyl or -alkynyl or (C3-C6)cycloalkyl, R3 and R4 are H, (subst.) (C1-C4)alkyl or (subst.) (C1-C4)alkoxy or halogen, (C1-C4)alkylthio, (C1-C4)- alkylamino or di[(C1-C4)alkyl]-amino, R5 is H or (C1-C4)alkyl and R6 is hydrogen, may be prepared by reacting compounds of the formula II, R1-X-R7 (II) with compounds of the formulae III, IV and V R6-OCN (III) SO2Cl2 (IV) Image (V) where R7 and R8 are H, a quarternary ammonium ion or one equivalent of a metal cation. The structure of the intermediate compounds has not been determined.

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