A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 36/74 (2006.01) A61K 36/539 (2006.01) A61K 36/82 (2006.01)
Patent
CA 2577355
The present invention relates to a composition for the prevention or treatment of physiological and pathological disorders mediated by cyclooxygenase (COX) and/or 5 -lipoxygenase (5-LO) comprising Uncaria genus plant, in particular, Uncaria gambir, or its extract, and to a combined composition of said Uncaria genus plant extract and Scutellaria baicalensis extract and/or Camellia sinensis extract. The present composition shows excellent COX and/5-LO inhibition effects, and thus can be used for the prevention or treatment of disease and disorders mediated by various COX pathway and/or 5-LO pathway, including osteoarthritis and rheumatoid arthritis.
La présente invention a trait à une composition pour la prévention ou le traitement de troubles physiologiques et pathologiques médiés par la cyclooxygénase (COX) et/ou la 5-lipoxygénase (5-LOX) comportant une plante du genre Uncaria, notamment, Uncaria gambir, ou son extrait, et à une composition combinée dudit extrait de plante du genre Uncaria et d'extrait de Scutellaria baicalensis et/ou d'extrait de Camellia sinensis. La composition de l'invention présente d'excellents effets d'inhibition de COX et/ou de 5-LOX, et peut ainsi être utilisée pour la prévention ou le traitement de maladie et de troubles médiés par diverses voie COX et/ou voie 5-LOX, comprenant l'arthrose et la polyarthrite rhumatoïde.
Cha Ji-Min
Do Seon-Gil
Jo Tae-Hyung
Kim Dong-Seon
Kim Jong-Han
Robic
Unigen Inc.
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