N-cyclohexylaminocarbonyl benzenesulfonamide derivatives

Details N-cyclohexylaminocarbonyl benzenesulfonamide derivatives N-cyclohexylaminocarbonyl benzenesulfonamide derivatives

C - Chemistry, Metallurgy

07

C

C07C 311/59 (2006.01) A61K 31/64 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2512879

A class of N-cyclohexylaminocarbonyl benzenesulfonamide derivatives are agonists or partial agonists or antagonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

L'invention concerne une classe de dérivés de N-cyclohexylaminocarbonyl benzenesulfonamide qui sont des agonistes ou des agonistes partiels ou des antagonistes du PPAR gamma et sont utiles dans le traitement et le contrôle de l'hyperglycémie qui est symptomatique des diabètes de type II, ainsi que de la dyslipidémie, de l'hyperlipidémie, hypercholestérolémie, hypertriglycéridémie, et de l'obésité qui sont souvent associées aux diabètes de type 2.

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