Phycotoxins and uses thereof

Details Phycotoxins and uses thereof Phycotoxins and uses thereof

A - Human Necessities

61

K

A61K 31/505 (2006.01)

Patent

CA 2606530

Pharmaceutical compositions for interfering with neuronal transmission comprising an effective amount of at least one tricyclic 3,4- propinoperhydropurine and at least one additional compound are disclosed. Preparations for topical applications are provided that comprise an effective amount of the composition of the invention and a pharmacologically acceptable carrier. Methods of interfering with neuronal transmission comprising topical application of an effective amount of the at least one tricyclic 3,4- propinoperhydropurine are provided for treatment of a variety of indications that relate to muscle relaxation, anesthesia, muscle spasms and similar causes.

Compositions pharmaceutiques pour interférer dans la transmission neuronale comprenant une quantité efficace d~au moins un tricyclique 3, 4 propinoperhydropurine et au moins un composé additionnel sont divulgués. Les préparations pour les applications topiques fournies comprenant une quantité efficace de la composition de l~invention et un support acceptable au niveau de la pharmacologie. Les méthodes d~interférence avec la transmission neuronale comprenant l~application typique d~une quantité efficace d~au moins un tricyclique 3, 4-propinoperhydropurine sont indiqués pour le traitement de différentes indications liées à la relaxation des muscles, l~anesthésie, aux spasmes musculaires et à des causes similaires.

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