Use of bactericidal/permeability increasing protein or...

Details Use of bactericidal/permeability increasing protein or... Use of bactericidal/permeability increasing protein or...

A - Human Necessities

61

K

A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01) F02B 75/02 (2006.01)

Patent

CA 2048619

The present invention provides a method of inhibiting lipopolysaccharide (LPS)- mediated stimulation of cells. This method comprises contacting the cells, in the presence of a cell-stimulating amount of lipopolysaccharide, with Bactericidal/Permeability Increasing Protein (BPI) in an amount effective to inhibit cell stimulation.

La présente invention concerne un procédé permettant d'inhiber la stimulation induite par lipopolysaccharides (LPS) des cellules, qui consiste à contacter les cellules, en présence d'une quantité stimulante de lipopolysaccharide, avec une protéine bactéricide/accroissant la perméabilité (BPI) en une quantité suffisante pour inhiber la stimulation de cellules.

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