Dosage forms providing controlled release of cholesteryl...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/40 (2006.01) A61K 31/4706 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2534371

A dosage form comprises a cholesteryl ester transfer protein inhibitor in a solubility-improved form and an HMG-CoA reductase inhibitor, wherein the dosage form provides immediate release of the HMG-CoA reductase inhibitor and controlled release of the cholesteryl ester transfer protein inhibitor.

Forme posologique comportant un inhibiteur de la protéine de transfert d'ester de cholestéryle sous une forme dont la solubilité est améliorée, ainsi qu'un inhibiteur de la HMG-CoA-réductase, ladite forme posologique étant adaptée pour assurer la libération immédiate de l'inhibiteur de la HMG-CoA-réductase ainsi qu'une libération contrôlée de l'inhibiteur de la protéine de transfert d'ester de cholestéryle.

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