Mitotic kinesin inhibitors

Details Mitotic kinesin inhibitors Mitotic kinesin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 211/70 (2006.01)

Patent

CA 2509212

The present invention relates to tetrahydropyridine compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

La présente invention concerne des composés de tétrahydropyridine utilisés pour traiter des maladies prolifératives cellulaires et des troubles liés à l'activité de la kinésine (KSP), et inhiber la kinésine (KSP). Cette invention a également trait à des compositions qui renferment ces composés et à leurs méthodes d'utilisation afin de traiter un cancer chez des mammaliens.

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