A ph sensitive potassium channel in spermatocytes

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/11 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01) G01N 33/84 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2307062

The invention provides isolated nucleic acid and amino acid sequences of Slo3, a pH sensitive potassium channel expressed in sperm; antibodies to Slo3; methods of screening for Slo3 inhibitors; and methods of screening for Slo3 homologs.

Cette invention concerne des séquences d'acide nucléique et d'acide aminé isolées de Slo3, un canal à potassium sensible au pH exprimé dans du sperme, des anticorps dirigés contre Slo3, des procédés de criblage d'inhibiteurs de Slo3; ainsi que des procédés de criblage d'homologues de Slo3.

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